USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: H2B1D_HUMAN USC-OGP 2-DE database:  H2B1D_HUMAN H2B1D_HUMAN General information about the entry View entry in simple text format Entry name H2B1D_HUMAN Primary accession number P58876 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Histone H2B type 1-D; AltName: Full=HIRA-interacting protein 2; AltName: Full=Histone H2B.1 B; AltName: Full=Histone H2B.b; Short=H2B/b;. Gene name Name=HIST1H2BD Synonyms=H2BFB, HIRIP2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1329: pI=4.39; Mw=16914 Cross-references UniProtKB/Swiss-Prot P58876; H2B1D_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name H2B1D_HUMAN Primary accession number P58876 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 145) Name and origin of the protein Description RecName: Full=Histone H2B type 1-D; AltName: Full=HIRA-interacting protein 2; AltName: Full=Histone H2B.1 B; AltName: Full=Histone H2B.b; Short=H2B/b; Gene name Name=HIST1H2BD Synonyms=H2BFB, HIRIP2 Encoded on Name=HIST1H2BD; Synonyms=H2BFB, HIRIP2 Keywords Acetylation; Chromosome; Complete proteome; Direct protein sequencing; DNA-binding; Glycoprotein; Isopeptide bond; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AJ223353; CAA11277.1; -; mRNA EMBL M60751; AAA63190.1; -; Genomic_DNA EMBL AF531287; AAN06687.1; -; Genomic_DNA EMBL AL353759; CAC04133.1; -; Genomic_DNA EMBL BC002842; AAH02842.1; -; mRNA CCDS CCDS4587.1; -; . PIR F40335; F40335; . RefSeq NP_066407.1; NM_021063.3; . RefSeq NP_619790.1; NM_138720.2; . UniGene Hs.591797; -; . ProteinModelPortal P58876; -; . SMR P58876; -; . BioGrid 109270; 17; . IntAct P58876; 8; . MINT MINT-4824521; -; . STRING 9606.ENSP00000289316; -; . iPTMnet P58876; -; . PhosphoSitePlus P58876; -; . SwissPalm P58876; -; . BioMuta HIST1H2BD; -; . DMDM 21542074; -; . MaxQB P58876; -; . PaxDb P58876; -; . PeptideAtlas P58876; -; . PRIDE P58876; -; . TopDownProteomics P58876; -; . Ensembl ENST00000289316; ENSP00000289316; ENSG00000158373; . Ensembl ENST00000377777; ENSP00000367008; ENSG00000158373; . GeneID 3017; -; . KEGG hsa:3017; -; . UCSC uc003ngr.4; human; . CTD 3017; -; . DisGeNET 3017; -; . DisGeNET 8339; -; . DisGeNET 8343; -; . DisGeNET 8344; -; . DisGeNET 8346; -; . DisGeNET 8347; -; . GeneCards HIST1H2BD; -; . H-InvDB HIX0005640; -; . HGNC HGNC:4747; HIST1H2BD; . HPA CAB062336; -; . HPA HPA042205; -; . HPA HPA043013; -; . HPA HPA048671; -; . MIM 602799; gene; . neXtProt NX_P58876; -; . OpenTargets ENSG00000158373; -; . PharmGKB PA29122; -; . eggNOG KOG1744; Eukaryota; . eggNOG ENOG4111NV5; LUCA; . GeneTree ENSGT00760000118976; -; . HOGENOM HOG000231213; -; . HOVERGEN HBG007774; -; . InParanoid P58876; -; . KO K11252; -; . OMA ARSCNSS; -; . OrthoDB EOG091G0XGD; -; . PhylomeDB P58876; -; . TreeFam TF300212; -; . Reactome R-HSA-1221632; Meiotic synapsis; . Reactome R-HSA-171306; Packaging Of Telomere Ends; . Reactome R-HSA-201722; Formation of the beta-catenin:TCF transactivating complex; . Reactome R-HSA-212300; PRC2 methylates histones and DNA; . Reactome R-HSA-2299718; Condensation of Prophase Chromosomes; . Reactome R-HSA-2559580; Oxidative Stress Induced Senescence; . Reactome R-HSA-2559582; Senescence-Associated Secretory Phenotype (SASP); . Reactome R-HSA-2559586; DNA Damage/Telomere Stress Induced Senescence; . Reactome R-HSA-3214815; HDACs deacetylate histones; . Reactome R-HSA-3214847; HATs acetylate histones; . Reactome R-HSA-427359; SIRT1 negatively regulates rRNA Expression; . Reactome R-HSA-427389; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; . Reactome R-HSA-427413; NoRC negatively regulates rRNA expression; . Reactome R-HSA-5250924; B-WICH complex positively regulates rRNA expression; . Reactome R-HSA-5334118; DNA methylation; . Reactome R-HSA-5578749; Transcriptional regulation by small RNAs; . Reactome R-HSA-5617472; Activation of anterior HOX genes in hindbrain development during early embryogenesis; . Reactome R-HSA-5625886; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-5693565; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; . Reactome R-HSA-5693571; Nonhomologous End-Joining (NHEJ); . Reactome R-HSA-5693607; Processing of DNA double-strand break ends; . Reactome R-HSA-606279; Deposition of new CENPA-containing nucleosomes at the centromere; . Reactome R-HSA-69473; G2/M DNA damage checkpoint; . Reactome R-HSA-73728; RNA Polymerase I Promoter Opening; . Reactome R-HSA-73777; RNA Polymerase I Chain Elongation; . Reactome R-HSA-8866654; E3 ubiquitin ligases ubiquitinate target proteins; . Reactome R-HSA-912446; Meiotic recombination; . Reactome R-HSA-977225; Amyloid fiber formation; . ChiTaRS HIST1H2BD; human; . GeneWiki HIST1H2BD; -; . GenomeRNAi 3017; -; . PRO PR:P58876; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000158373; -; . CleanEx HS_HIST1H2BD; -; . ExpressionAtlas P58876; baseline and differential; . Genevisible P58876; HS; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0000786; C:nucleosome; IEA:UniProtKB-KW; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0003677; F:DNA binding; IBA:GO_Central; . GO GO:0006334; P:nucleosome assembly; IBA:GO_Central; . GO GO:0016567; P:protein ubiquitination; TAS:Reactome; . Gene3D 1.10.20.10; -; 1; . InterPro IPR009072; Histone-fold; . InterPro IPR007125; Histone_H2A/H2B/H3; . InterPro IPR000558; Histone_H2B; . PANTHER PTHR23428; PTHR23428; 1; . Pfam PF00125; Histone; 1; . PRINTS PR00621; HISTONEH2B; . SMART SM00427; H2B; 1; . SUPFAM SSF47113; SSF47113; 1; . PROSITE PS00357; HISTONE_H2B; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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